The Applicability of the Gail Model in Iranian Population

نویسندگان

  • Keivan Majidzadeh-A Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  • Leila Farahmand Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  • Massoome Najafi Division of Surgical Oncology, Department of Surgery, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
چکیده مقاله:

Introduction: Gail model is one of the most important models for the evaluation of breast cancer risk between US white females. According to genetic diversity, there is a possibility of affecting the efficiency of the Gail model in risk assessment of breast cancer among Iranian populations. In this study, the Gail model efficiency in specifying the risk of breast cancer in Iranian population was evaluated. Methods: This was a case-control study. The case group was formed of the referrals to Breast Cancer Research Center, Academic Center for Education Culture and Research (ACECR), who were affected by different types of aggressive cancer. Results: A total of 416 patients with breast cancer and the same number in the control group were considered during the study. There were no meaningful statistical differences in age at menarche, age at first live birth, and nulliparous women between case and control groups. The average of five-year risk of breast cancer in the case and control groups had no statistically significant difference. Chemoprevention was only eligible for 7.2% of the patients based on 1.67% five-year risk. In addition, there was no statistically meaningful difference between comparative risk and breast cancer risk in a lifetime. Conclusions: The low risks estimated by the Gail model among patients with breast cancer as well as the absence of meaningful statistical difference in the estimated risks by this model between the case and control groups showed that the Gail model had insufficient efficiency in determining breast cancer risk in the Iranian society.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the applicability of the gail model in iranian population

introduction: gail model is one of the most important models for the evaluation of breast cancer risk between us white females. according to genetic diversity, there is a possibility of affecting the efficiency of the gail model in risk assessment of breast cancer among iranian populations. in this study, the gail model efficiency in specifying the risk of breast cancer in iranian population wa...

متن کامل

the effect of learning strategies on the speaking ability of iranian students in the context of language institutes

the effect of learning strategies on the speaking ability of iranian students in the context of language institutes abstract language learning strategies are of the most important factors that help language learners to learn a foreign language and how they can deal with the four language skills specifically speaking skill effectively. acknowledging the great impact of learning strategies...

learners’ attitudes toward the effectiveness of mobile-assisted language learning (mall) in vocabulary acquisition in the iranian efl context: the case of word lists, audiobooks and dictionary use

رشد انفجاری تکنولوژی فرصت های آموزشی مهیج و جدیدی را پیش روی فراگیران و آموزش دهندگان گذاشته است. امروزه معلمان برای اینکه در امر آموزش زبان بروز باشند باید روش هایی را اتخاذ نمایند که درآن ها از تکنولوژی جهت کمک در یادگیری زبان دوم و چندم استفاده شده باشد. با در نظر گرفتن تحولاتی که رشته ی آموزش زبان در حال رخ دادن است هم اکنون زمان مناسبی برای ارزشیابی نگرش های موجود نسبت به تکنولوژی های جدید...

15 صفحه اول

the place of iranian public diplomacy in central asia

چکیده: نسبت به کارکرد و ماهیت دیپلماسی عمومی در جهان امروز نظریه های متعددی بیان گردیده و جایگاه آن در کنار نظریه های دیگر در محافل آکادمیک و دانشگاهی بررسی و تحلیل گردیده است. نظر به اهمیت دیپلماسی عمومی و جایگاه آن در سیاست خارجی ایران این نوشتار با تمرکز بر دیپلماسی عمومی در منطقه آسیای مرکزی تهیه و تنظیم شده است. این ضرورت از آنجا ناشی می شود که اولاً مفهوم دیپلماسی عمومی در سیاست خارجی ای...

15 صفحه اول

the impact of morphological awareness on the vocabulary development of the iranian efl students

this study investigated the impact of explicit instruction of morphemic analysis and synthesis on the vocabulary development of the students. the participants were 90 junior high school students divided into two experimental groups and one control group. morphological awareness techniques (analysis/synthesis) and conventional techniques were used to teach vocabulary in the experimental groups a...

15 صفحه اول

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 1  شماره None

صفحات  13- 19

تاریخ انتشار 2017-04

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023